|
KMID : 1155220240490010001
|
|
Journal of the Korean Society of Health Information and Health Statistics
2024 Volume.49 No. 1 p.1 ~ p.8
|
|
|
Statistical Methodologies for Detecting Drug-Drug Interaction Using Spontaneous Reporting System
|
|
Won Hee-Hyun
Cho Hae-Rin
Choi Hyun-Young
Choi Nam-Kyong
|
|
|
Abstract
|
|
|
|
Statistical methodologies of signal detection for drug-drug interactions (DDIs) have been developed and used. In this study, we review methodologies for DDI signal detection using the spontaneous reporting system. We describe the characteristics of the additive and multiplicative risk model, logistic regression model, Multi-item Gamma-Poisson Shrinker, Ω shrinkage measure model, and Chi-square statistics model. We discuss the advantages and disadvantages of each methodology along with examples, providing researchers with information to choose the most appropriate methodology for their study.
|
|
|
KEYWORD
|
|
|
Drug interactions, Signal detections, Adverse Drug Reaction Reporting System
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|